Melatonin For Sleep Diss

br br br brbr Entrez PubMedbr brbr brp br br brbr br br br br My NCBI[Sign In] [Register]br br br br All Databases PubMed Nucleotide Protein Genome coordinate OMIM PMC Journals Books Search PubMed Protein Nucleotide CoreNucleotide GSS EST coordinate Genome Books CancerChromosomes Conserved Domains dbGaP 3D Domains Gene Genome Project GENSAT br GEO Pros GEO DataSets HomoloGene Journals ignition interlock NCBI Web Site NLM Catalog OMIA OMIM PMC PopSet Probe Protein Clusters PubChem BioAssay PubChem commingle PubChem nerve centre SNP Taxonomy ToolKit UniGene UniSTS for br br br br br br br br br br br br br br br br br Limits br br br Preview /Index br br br History br br br Clipboard br br br Details Display epitome Brief Abstract AbstractPlus Citation MEDLINE XML UI List LinkOut ASN .1 Related Articles Cited Articles Cited in Books CancerChrom think Domain tie in 3D Domain think GEO DataSet link up Gene links Gene (GeneRIF ) Links Genome Links Project Links GENSAT Links GEO Pro Links HomoloGene Links Nucleotide Links Nucleotide (RefSeq ) Links OMIA Links OMIM (calculated ) Links OMIM (cited ) Links BioAssay Links mixed Links Compound via MeSH Substance Links Substance via MeSH Substance (Publisher ) Links PMC Links Cited in PMC PopSet Links Probe Links Protein Links Protein (RefSeq ) Links Protein Cluster Links SNP Links Structure Links Taxonomy via GenBank UniGene Links UniSTS Links Show 5 10 20 50 100 200 500br Sort by Pub Date First fountain Last Author Journalbr Send to Text br Printer Clipboard E-mail brbr br br br br br All : 1 br br Review : 0 br brbr br br br 1 : eternal stop . 2006 May 1 29 (5 :609-18Links Comment in Sleep . 2006 May 1 29 (5 :606-7Sleep-facilitating effect of exogenous melatonin in healthy youngish men and women is circadian-phase dependent Wyatt JK Dijk DJ Ritz-de Cecco A Ronda JM Czeisler CADivision of Sleep medicinal drug , Department of Medicine , Brigham and Women a Hospital Division of Sleep Medicine , Harvard Medical School , Boston , MA , the States . jwyatt rush .edu STUDY OBJECTIVES : To investigate the effects of a physiological and a pharmacologic dose of exogenous melatonin on peacefulness latency and rest period ability in calm fortunes initiated crossways a teeming range of circadian phases . DESIGN : Double-blind placebo-controlled parallel-group plan in a 27-day forced desynchrony paradigm with a 20-hour plan sleep-wake cycle .

SETTING : Private suite of a worldwide clinical research center , in the absence of time-of-day tuition . Subjects : Thirty-six healthy , 18- to 30-year-old , men (n 21 ) and women (n 15 . INTERVENTIONS : viva voce melatonin (0 .3 mg or 5 .0 mg ) or identical-appearing placebo was administered 30 minutes prior to each 6 .67-hour sleep episode during forced desynchrony . MEASUREMENTS AND RESULTS : Both doses of melatonin improved polysomnographically determined sleep efficiency from 77 in the placebo group to 83 for sleep episodes occurring during circadian phases when endogenous melatonin was absent . However , this remained below the average sleep efficiency of 88 observed during sleep episodes scheduled during the circadian darkness , when endogenous melatonin was present . Melatonin did not significantly come upon sleep initiation or core body temperature . Melatonin appeared to manage efficacy across the study and did not significantly uphold percentages of slow-wave sleep or rapid eye movement sleep . CONCLUSIONS : Exogenous melatonin administration possesses circadian-phase-dependent hypnotic properties , allowing for improved consolidation of sleep that occurs out of phase with endogenous melatonin secretion during the circadian night . The results support the hypothesis that...If you want to get a full essay, order it on our website: Orderessay

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